Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
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DOI: 10.1038/s41467-019-08585-4
Abstract: Insulin-induced gene (Insig) negatively regulates SREBP-mediated de novo fatty acid synthesis in the liver. However, the upstream regulation of Insig is incompletely understood. Here we report that AMPK interacts with and mediates phosphorylation of Insig.… read more here.
Keywords: insig; induced gene; ampk dependent; gene ... See more keywords