Articles with "insig1" as a keyword



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Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression

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Published in 2021 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2021.101210

Abstract: Objective Non-alcoholic fatty liver disease (NAFLD) is a silent pandemic associated with obesity and the metabolic syndrome, and also increases cardiovascular- and cirrhosis-related morbidity and mortality. A complete understanding of adaptive compensatory metabolic programmes that… read more here.

Keywords: nash progression; suppression insulin; insig1; progression ... See more keywords