Hepatoprotective Effect of Trehalose: Insight into Its Mechanisms of Action.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-73234-9_34
Abstract: Trehalose is a nonreducing disaccharide formed by two glucose molecules. It has been shown that trehalose can protect proteins and cellular membranes against the adverse effects of different types of stress, such as dehydration, cold,… read more here.
Keywords: trehalose insight; insight mechanisms; action; hepatoprotective effect ... See more keywords
A Comprehensive Insight into the Mechanisms of Dopamine in Disrupting Aβ Protofibrils and Inhibiting Aβ Aggregation.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00306
Abstract: Fibrillary aggregates of amyloid-β (Aβ) are the pathological hallmark of Alzheimer's disease (AD). Clearing Aβ deposition or inhibiting Aβ aggregation is a promising approach to treat AD. Experimental studies reported that dopamine (DA), an important… read more here.
Keywords: aggregation; inhibiting aggregation; insight mechanisms; dopamine disrupting ... See more keywords
Mitochondrial function in the heart: the insight into mechanisms and therapeutic potentials
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14431
Abstract: Mitochondrial dysfunction is considered as a crucial contributory factor in cardiac pathology. This has highlighted the therapeutic potential of targeting mitochondria to prevent or treat cardiac disease. Mitochondrial dysfunction is associated with aberrant electron transport… read more here.
Keywords: mechanisms therapeutic; mitochondrial function; insight mechanisms; therapeutic potentials ... See more keywords
Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Circulation research"
DOI: 10.1161/circresaha.122.319950
Abstract: Stroke is the second leading cause of death worldwide and a complex, heterogeneous condition. In this review, we provide an overview of the current knowledge on monogenic and multifactorial forms of stroke, highlighting recent insight… read more here.
Keywords: stroke genetics; genetics; insight mechanisms; discovery insight ... See more keywords
New Insight Into Mechanisms of Hepatic Encephalopathy: An Integrative Analysis Approach to Identify Molecular Markers and Therapeutic Targets
Sign Up to like & getrecommendations! Published in 2023 at "Bioinformatics and Biology Insights"
DOI: 10.1177/11779322231155068
Abstract: Hepatic encephalopathy (HE) is a set of complex neurological complications that arise from advanced liver disease. The precise molecular and cellular mechanism of HE is not fully understood. Differentially expressed genes (DEGs) from microarray technologies… read more here.
Keywords: hepatic encephalopathy; encephalopathy integrative; insight mechanisms; analysis ... See more keywords