Molecular Insights into Compound-Transporter Interactions: The Case of Inhibitors of Gram-Negative Bacteria Efflux Pumps
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DOI: 10.1016/j.bpj.2016.11.1483
Abstract: The Escherichia coli AcrAB-TolC efflux pump is the archetype of the Resistance-Nodulation-cell Division (RND) exporters from Gram-negative bacteria. Overexpression of RND-type efflux pumps is a major factor in multidrug resistance (MDR), which makes these polyspecific… read more here.
Keywords: gram negative; compound transporter; negative bacteria; molecular insights ... See more keywords