Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel
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DOI: 10.1016/j.neuron.2019.11.023
Abstract: Transient receptor potential channel subfamily A member 1 (TRPA1) is a Ca2+-permeable cation channel that serves as one of the primary sensors of environmental irritants and noxious substances. Many TRPA1 agonists are electrophiles that are… read more here.
Keywords: insights electrophile; trpa1; structural insights; channel ... See more keywords