New insights into FAK structure and function in focal adhesions.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cell science"
DOI: 10.1242/jcs.259089
Abstract: Focal adhesion kinase (FAK; also known as PTK2) was discovered three decades ago and is now recognised as a key player in the regulation of cell-matrix adhesion and mesenchymal cell migration. Although it is essential… read more here.
Keywords: new insights; cell; structure function; fak structure ... See more keywords
New insights on Fak and Fak inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Current medicinal chemistry"
DOI: 10.2174/0929867327666201103162239
Abstract: BACKGROUND Focal adhesion kinase (Fak) is a cytoplasmic protein tyrosine kinase overexpressed and activated in different solid cancer; it showed important role in metastasis formation, cell migration, invasion and angiogenesis and consequently it has been… read more here.
Keywords: chemical scaffolds; chemistry; insights fak; new insights ... See more keywords