Species-Spanning Echocardiography: Cardiovascular Insights from Across the Animal Kingdom
Sign Up to like & getrecommendations! Published in 2020 at "Current Cardiology Reports"
DOI: 10.1007/s11886-020-01417-8
Abstract: The objective of this review is to present comparative echocardiography as a source of insights for human cardiovascular medicine. We present echocardiographic examples of high impact human cardiovascular pathologies, including valvular, vascular, conduction, and myocardial… read more here.
Keywords: species spanning; medicine; spanning echocardiography; cardiology ... See more keywords
Three-dimensional insights into human enveloped viruses in vitro and in situ
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society Transactions"
DOI: 10.1042/bst20210433
Abstract: Viruses can be enveloped or non-enveloped, and require a host cell to replicate and package their genomes into new virions to infect new cells. To accomplish this task, viruses hijack the host-cell machinery to facilitate… read more here.
Keywords: dimensional insights; cryo; insights human; three dimensional ... See more keywords
Structural insights into the human PA28–20S proteasome enabled by efficient tagging and purification of endogenous proteins
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207200119
Abstract: Significance We report an approach of combining CRISPR-Cas9 gene editing with florescence cell sorting to tag and purify human endogenous protein complexes from HEK cells for structural studies by single-particle cryogenic electron microscopy. This procedure… read more here.
Keywords: 20s proteasome; human pa28; structural insights; insights human ... See more keywords
Recent insights into human bronchial proteomics – how are we progressing and what is next?
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2017.1417847
Abstract: ABSTRACT Introduction: The human respiratory system is highly prone to diseases and complications. Many lung diseases, including lung cancer (LC), tuberculosis (TB), and chronic obstructive pulmonary disease (COPD) have been among the most common causes… read more here.
Keywords: proteomics progressing; human bronchial; recent insights; insights human ... See more keywords
Insights Into Human and Nonhuman Primate Handedness From Measuring Both Hands
Sign Up to like & getrecommendations! Published in 2022 at "Current Directions in Psychological Science"
DOI: 10.1177/09637214211062876
Abstract: Handedness is part of our everyday lives, but where does it come from? Researchers studying nonhuman primates and young children have approached this question from different perspectives—evolutionary and developmental, respectively. Their work converges on the… read more here.
Keywords: nonhuman primate; primate handedness; insights human; measuring hands ... See more keywords
Insights into the Human Microbiome and Its Connections with Prostate Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092539
Abstract: Simple Summary In recent years, numerous research studies have been conducted to investigate the microorganisms encountered in various systems of the human body and their implications for cancer development and progression. This review offers a… read more here.
Keywords: prostate cancer; microbiome connections; insights human; human microbiome ... See more keywords
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147950
Abstract: Human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms IX and XII are overexpressed in solid hypoxic tumors, and they are considered as prognostic tools and therapeutic targets for cancer. Based on a molecular simplification of the… read more here.
Keywords: human carbonic; carbonic anhydrase; insights human; design ... See more keywords
Photovoice for mobilizing insights on human well-being in complex social-ecological systems: case studies from Kenya and South Africa
Sign Up to like & getrecommendations! Published in 2018 at "Ecology and Society"
DOI: 10.5751/es-10259-230313
Abstract: The value of diverse perspectives in social-ecological systems research and transdisciplinarity is well recognized. Human well-being and how it is derived from dynamic ecosystems is one area where ... read more here.
Keywords: ecological systems; mobilizing insights; human well; photovoice mobilizing ... See more keywords
Structural and functional insights of the human peroxisomal ABC transporter ALDP
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.75039
Abstract: Adrenoleukodystrophy protein (ALDP) is responsible for the transport of very-long-chain fatty acids (VLCFAs) and corresponding CoA-esters across the peroxisomal membrane. Dysfunction of ALDP leads to peroxisomal metabolic disorder exemplified by X-linked adrenoleukodystrophy (ALD). Hundreds of… read more here.
Keywords: functional insights; peroxisomal abc; insights human; abc transporter ... See more keywords