Insights image for Forskolin attenuates the NLRP3 inflammasome activation and IL-1β secretion in human macrophages
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DOI: 10.1038/s41390-019-0544-z
Abstract: Nigericin activates the NLRP3 inflammasome by stimulating an intracellular K+ efflux through the pannexin-1 dependent pathway, which induces the assembly of the NLRP3 inflammasome (NLRP3-ASC-Caspase 1) and its subsequent activation of the secretion of IL-1β… read more here.
Keywords: caspase; insights image; secretion; activation secretion ... See more keywords
Insights Image for “Repetitive noxious stimuli during early development affect acute and long-term mechanical sensitivity in rats”
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DOI: 10.1038/s41390-019-0575-5
Abstract: Anatomy of the adult pain pathway. Primary afferent fibers transmit nociceptive information to the spinal cord dorsal horn. Here, the nociceptive signal is conveyed to projection neurons, transmitting the information to supraspinal areas. Signals arriving… read more here.
Keywords: insights image; noxious stimuli; pain; repetitive noxious ... See more keywords
Insights Image for “Effect of prebiotic and probiotic supplementation on neurodevelopment in preterm very low birth weight infants: findings from a meta-analysis”
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DOI: 10.1038/s41390-019-0616-0
Abstract: Received: 13 August 2019 Revised: 13 August 2019 Accepted: 13 August 2019 Centre for Health Research and Development, Society for Applied Studies, New Delhi, India; Centre for Intervention Science in Maternal and Child Health, Centre… read more here.
Keywords: insights image; effect prebiotic; august 2019; probiotic supplementation ... See more keywords
Insights Image for “Hyaluronan 35 kDa enhances epithelial barrier function and protects against the development of murine necrotizing enterocolitis”
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DOI: 10.1038/s41390-020-0773-1
Abstract: Received: 15 January 2020 Accepted: 15 January 2020 Department of Neonatal and Perinatal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of GI/Liver Pathology, UCLA, Los Angeles, CA, USA; Department of… read more here.
Keywords: insights image; pathology; image hyaluronan; department ... See more keywords