Insights into the immune manipulation mechanisms of pollen allergens by protein domain profiling
Sign Up to like & getrecommendations! Published in 2017 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2017.07.006
Abstract: Plant pollens are airborne allergens, as their inhalation causes immune activation, leading to rhinitis, conjunctivitis, sinusitis and oral allergy syndrome. A myriad of pollen proteins belonging to profilin, expansin, polygalacturonase, glucan endoglucosidase, pectin esterase, and… read more here.
Keywords: immune manipulation; protein domain; insights immune; immune system ... See more keywords
Abstract 6705: An integratedin vitroandin vivoapproach providing insights in immune modulation
Sign Up to like & getrecommendations! Published in 2020 at "Immunology"
DOI: 10.1158/1538-7445.am2020-6705
Abstract: In order to exploit the complex tumour microenvironment, immunoreactivity in a multitude of cell-based assays is required to predict mode of action (MOA), pharmacodynamics, and efficacy downstream. We have developed an integrated approach starting with… read more here.
Keywords: insights immune; immune modulation; target; oncology ... See more keywords
Mechanistic Insights Into the Immune Pathophysiology of COVID-19; An In-Depth Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.835104
Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In addition to the respiratory manifestations seen in severe cases, multi-organ pathologies also occur, making management a much-debated… read more here.
Keywords: review; insights immune; cytokine storm; covid ... See more keywords
New Insights into Immune-Mediated Mechanisms in Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21239302
Abstract: The immune system has been increasingly recognized as a major contributor in the pathogenesis of Parkinson’s disease (PD). The double-edged nature of the immune system poses a problem in harnessing immunomodulatory therapies to prevent and… read more here.
Keywords: immune; insights immune; immune mediated; parkinson disease ... See more keywords