Molecular insights into the multifaceted functions and therapeutic targeting of high mobility group box 1 in metabolic diseases
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DOI: 10.1111/jcmm.17448
Abstract: HMGB1 is a ubiquitously expressed protein localized in nucleus, cytoplasm, as well as secreted into extracellular space. Nuclear HMGB1 binds to DNAs and RNAs, regulating genomic stability and transcription. Cytoplasmic HMGB1 regulates autophagy through binding… read more here.
Keywords: molecular insights; metabolic diseases; insights multifaceted; functions therapeutic ... See more keywords