Neurobiological insights and novel therapeutic opportunities for CNS disorders from mGlu receptor allosteric and biased modulation
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2016.10.007
Abstract: HIGHLIGHTSSelective ligands have helped define the neurobiological roles of mGlu receptors.Biased agonism/modulation is a key feature of mGlu signaling.Biased signaling should inform future mGlu drug discovery programs. &NA; The metabotropic glutamate (mGlu) receptor family is… read more here.
Keywords: modulation; neurobiological insights; mglu receptor; cns disorders ... See more keywords
Biochemical insights into a novel thermo/organo tolerant bilirubin oxidase from Thermosediminibacter oceani and its application in dye decolorization
Sign Up to like & getrecommendations! Published in 2020 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2019.09.030
Abstract: Abstract Higher activity and stability at neutral pH and tolerance toward anions have made bilirubin oxidases (BODs) proper candidates for industrial utilizations. A putative BOD from Thermosediminibacter oceani (ToBOD) exhibited high stability over a pH… read more here.
Keywords: bilirubin; thermosediminibacter oceani; insights novel; biochemical insights ... See more keywords
Insights into the novel application of Fe-MOFs in ultrasound-assisted heterogeneous Fenton system: Efficiency, kinetics and mechanism.
Sign Up to like & getrecommendations! Published in 2020 at "Ultrasonics sonochemistry"
DOI: 10.1016/j.ultsonch.2020.105411
Abstract: In this work, as a new strategy, ultrasound/H2O2/MOF system was firstly applied by environmental-benign Fe-MOFs (MIL-53, MIL-88B and MIL-101) for tetracycline hydrochloride removal. The syntheticFe-MOFs were characterized by XRD, FTIR, SEM, XPS, N2 sorption-desorption isotherms… read more here.
Keywords: mil 88b; system; insights novel; mofs ... See more keywords
Insights into a novel garnet-based yellowish-green phosphor: structure, luminescence properties and application for warm white light-emitting diodes
Sign Up to like & getrecommendations! Published in 2019 at "CrystEngComm"
DOI: 10.1039/c9ce01163c
Abstract: Efficient and stable yellowish-green emission has been achieved in the garnet-based phosphor CYAS:Ce3+. read more here.
Keywords: novel garnet; phosphor; yellowish green; insights novel ... See more keywords
Insights into a novel class of azobenzenes incorporating 4,6-O-protected sugars as photo-responsive organogelators
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra08033c
Abstract: A novel class of 4,6-O-butylidene/ethylidene/benzylidene β-d-glucopyranose gelator functionalized with photo-responsive azobenzene moieties were designed and synthesized and also characterized using different spectral techniques. read more here.
Keywords: azobenzenes incorporating; novel class; insights novel; class azobenzenes ... See more keywords
Molecular Insights and Novel Approaches toward Individualized Arteriovenous Fistula Care.
Sign Up to like & getrecommendations! Published in 2022 at "Blood purification"
DOI: 10.1159/000525831
Abstract: The aim of the paper is to summarize the current understanding of the molecular biology of arteriovenous fistula (AVF). It intends to encourage vascular access teams, care providers, and scientists, to explore new molecular tools… read more here.
Keywords: vascular access; arteriovenous fistula; novel approaches; molecular insights ... See more keywords
Deriving Analytic Insights During a Novel Pandemic
Sign Up to like & getrecommendations! Published in 2021 at "North Carolina Medical Journal"
DOI: 10.18043/ncm.82.4.284
Abstract: This paper summarizes the impact health care analytics has had on the COVID-19 pandemic from the combined perspectives of three North Carolina health systems: Vidant Health in Greenville, Duke Health in Durham, and Cone Health… read more here.
Keywords: novel pandemic; deriving analytic; analytic insights; health ... See more keywords
Hemophilia a patients with inhibitors: Mechanistic insights and novel therapeutic implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1019275
Abstract: The development of coagulation factor VIII (FVIII) inhibitory antibodies is a serious complication in hemophilia A (HA) patients after FVIII replacement therapy. Inhibitors render regular prophylaxis ineffective and increase the risk of morbidity and mortality.… read more here.
Keywords: hemophilia patients; inhibitors mechanistic; novel therapeutic; insights novel ... See more keywords
Mechanism and Structural Insights Into a Novel Esterase, E53, Isolated From Erythrobacter longus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.798194
Abstract: Esterases are a class of enzymes that split esters into an acid and an alcohol in a chemical reaction with water, having high potential in pharmaceutical, food and biofuel industrial applications. To advance the understanding… read more here.
Keywords: structural insights; region; insights novel; mechanism structural ... See more keywords
Molecular insights into novel environmental strains of Klebsiella quasipneumoniae harboring different antimicrobial-resistance genes
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.1068888
Abstract: Introduction The emergence of bacterial pathogens in environmental hosts represents a major risk to public health. This study aimed at characterizing seven novel environmental strains of K. quasipneumoniae using a genomic approach which was misidentified… read more here.
Keywords: strains klebsiella; environmental strains; klebsiella quasipneumoniae; novel environmental ... See more keywords
Taxonomic and Phylogenetic Insights into Novel Ascomycota from Forest Woody Litter
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11060889
Abstract: Simple Summary Studies suggest that fungi belonging to Ascomycota are sensitive to environmental changes which are disrupting ecosystems globally, with numerous extinction events, imbuing fungal diversity research with a sense of urgency. Thus, it is… read more here.
Keywords: taxonomic phylogenetic; woody litter; novel ascomycota; phylogenetic insights ... See more keywords