Novel insights in plasticity and learning impairments in Fragile X Syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Brain research bulletin"
DOI: 10.1016/j.brainresbull.2021.06.025
Abstract: The function of brain circuits relies on high-fidelity information transfer, precisely controlling integration of synaptic input, leading to neuronal output. Synaptic inputs arrive primarily at dendrites, where they undergo integration and summation throughout the somatodendritic… read more here.
Keywords: information; fragile syndrome; novel insights; plasticity learning ... See more keywords
Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain
Sign Up to like & getrecommendations! Published in 2021 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.0c00684
Abstract: The nsP3 macrodomain is a conserved protein interaction module that plays essential regulatory roles in the host immune response by recognizing and removing posttranslational ADP-ribosylation sites during SARS-CoV-2 infection. Thus targeting this protein domain may… read more here.
Keywords: macrodomain structural; cov macrodomain; structural insights; insights plasticity ... See more keywords