New insights into the role of microRNAs and long noncoding RNAs in most common neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28361
Abstract: Neurodegenerative diseases (NDs) are a diversity of neurological disorders characterized by the progressive degeneration of the structure and function of the central nervous system (CNS). The most common NDs are Alzheimer's disease (AD), Parkinson's disease… read more here.
Keywords: long noncoding; insights role; common nds; neurodegenerative diseases ... See more keywords
Mechanistic insights into the role of vitamin D and computational identification of potential lead compounds for Parkinson's disease
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30379
Abstract: Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects dopaminergic neurons in the midbrain. A recent study suggests that Orphan Nuclear Receptor 1 (NURR1) impairment may contribute to PD pathogenesis. Our study… read more here.
Keywords: role vitamin; disease; parkinson disease; insights role ... See more keywords
Novel insights into the role of circular RNAs in Parkinson disease: An emerging renaissance in the management of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25094
Abstract: Parkinson's disease (PD), as a debilitating neurodegenerative disease, particularly affects the elderly population, and is clinically identified by resting tremor, rigidity, and bradykinesia. Pathophysiologically, PD is characterized by an early loss of dopaminergic neurons in… read more here.
Keywords: disease; circular rnas; parkinson disease; insights role ... See more keywords
Mechanistic insights into the role of actinobacteria as potential biocontrol candidates against fungal phytopathogens.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of basic microbiology"
DOI: 10.1002/jobm.202300027
Abstract: Worldwide mounting demand for better food production to nurture exasperating population emphasizes on reduced crop losses. The incidence of pathogens into the agricultural fields has tend to dwindle plethora of cereal, vegetable, and other fodder… read more here.
Keywords: role actinobacteria; biocontrol; role; insights role ... See more keywords
Insights into the role of paraoxonase 2 in human pathophysiology
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biosciences"
DOI: 10.1007/s12038-021-00234-7
Abstract: Paraoxonase 2 (PON2) is a ubiquitously expressed intracellular enzyme that is known to have a protective role from oxidative stress. Clinical studies have also demonstrated the significance of PON2 in the manifestation of cardiovascular and… read more here.
Keywords: pon2; insights role; role paraoxonase; oxidative stress ... See more keywords
Recent insights into the role of glia and oxidative stress in Alzheimer's disease gained from Drosophila
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2021.07.012
Abstract: Here, we discuss findings made using Drosophila on Alzheimer's disease (AD) risk and progression. Recent studies have investigated the mechanisms underlying glia-mediated neuroprotection in AD. First, we discuss a novel mechanism of glial lipid droplet… read more here.
Keywords: made using; insights role; alzheimer disease; disease ... See more keywords
New insights on the role of alkaline phosphatase 2 from Spodoptera exigua (Hübner) in the action mechanism of Bt toxin Cry2Aa.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of insect physiology"
DOI: 10.1016/j.jinsphys.2016.12.004
Abstract: Cry1A and Cry2A toxins, which are widely used in Bt transgenic crops, can specifically bind to insect midguts and exert their insecticidal effects. There are interactions between insect midgut-binding proteins and Cry1A toxins; however, little… read more here.
Keywords: new insights; insights role; spodoptera exigua; exigua ... See more keywords
Insights into the role of hepatocyte PPARα activity in response to fasting
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.07.035
Abstract: The liver plays a central role in the regulation of fatty acid metabolism. Hepatocytes are highly sensitive to nutrients and hormones that drive extensive transcriptional responses. Nuclear hormone receptors are key transcription factors involved in… read more here.
Keywords: ppar; insights role; role hepatocyte; role ... See more keywords
New insights into the role and therapeutic potential of HSP70 in diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacological research"
DOI: 10.1016/j.phrs.2022.106173
Abstract: Emerging evidence indicates that HSP70 represents a key mechanism in the pathophysiology of β-cell dysfunction, insulin resistance, and various diabetic complications, including micro- and macro-vascular alterations, as well as impaired hemostasis. Hyperglycemia, a hallmark of… read more here.
Keywords: therapeutic potential; insights role; role therapeutic; potential hsp70 ... See more keywords
New insights into the role of solution additive anions in Mg2+ dehydration: implications for mineral carbonation
Sign Up to like & getrecommendations! Published in 2021 at "CrystEngComm"
DOI: 10.1039/d1ce00052g
Abstract: Computer simulations of the Mg2+ dehydration mechanism show that solution additives can stabilise undercoordinated Mg2+ hydration configurations, opening up coordination sites on the central Mg2+ ion, promoting Mg-carbonates nucleation and growth. read more here.
Keywords: dehydration; insights role; new insights; mg2 dehydration ... See more keywords
Molecular insights into the role of electronic cigarettes in oral carcinogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Critical Reviews in Toxicology"
DOI: 10.1080/10408444.2023.2190764
Abstract: Abstract Electronic cigarette (EC) usage or vaping has seen a significant rise in recent years across various parts of the world. They have been publicized as a safe alternative to smoking; however, this is not… read more here.
Keywords: role; role electronic; molecular insights; insights role ... See more keywords