Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma
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DOI: 10.1158/2159-8290.cd-22-0886
Abstract: Cancer cell genomic instability correlates with proinflammatory IL6 and IL8 production, VEGF, as well as regulatory T cells and is associated with primary resistance to immunotherapy and antiangiogenics in patients with advanced mesothelioma. read more here.
Keywords: primary resistance; genomic instability; instability protumoral; associated primary ... See more keywords