Enzyme-instructed self-assembly enabled fluorescence light-up for alkaline phosphatase detection.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.123078
Abstract: Alkaline phosphatase (ALP) exists in both normal and pathological tissues. Spatiotemporal variations in ALP levels can reveal its potential physiological functions and changes that occur during pathological conditions. However, it is still challenging to exploit… read more here.
Keywords: instructed self; self assembly; fluorescence; enzyme instructed ... See more keywords
Alkaline Phosphatase-Instructed Self-Assembly of Gadolinium Nanofibers for Enhanced T2-Weighted Magnetic Resonance Imaging of Tumor.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b00621
Abstract: Alkaline phosphatase (ALP) is an important enzyme but using ALP-instructed self-assembly of gadolinium nanofibers for enhanced T2-weighted magnetic resonance imaging (MRI) of tumor has not been reported. In this work, we rationally designed a hydrogelator… read more here.
Keywords: enhanced weighted; instructed self; gadolinium nanofibers; alkaline phosphatase ... See more keywords
Enzyme-Instructed Self-Assembly for Subcellular Targeting
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c02019
Abstract: Subcellular compartmentalization is a key feature of eukaryotic cells. Selectively targeting subcellular compartments, though holding many exciting opportunities for biomedicine, remains rather underdeveloped. Self-assembly provides a new way for subcellular targeting. In this mini-review, we… read more here.
Keywords: subcellular targeting; instructed self; self assembly; enzyme instructed ... See more keywords
Intracellular Enzyme-Instructed Self-Assembly of Peptides (IEISAP) for Biomedical Applications
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27196557
Abstract: Despite the remarkable significance and encouraging breakthroughs of intracellular enzyme-instructed self-assembly of peptides (IEISAP) in disease diagnosis and treatment, a comprehensive review that focuses on this topic is still desirable. In this article, we carefully… read more here.
Keywords: assembly peptides; self assembly; intracellular enzyme; enzyme instructed ... See more keywords