The metaplastic effects of NMDA receptors blockade on reactivation of instrumental memories in rats
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DOI: 10.1016/j.nlm.2018.01.007
Abstract: HIGHLIGHTSMK‐801 given 24h before instrumental memory retrieval affected reconsolidation.Changes of Zif268 and rpS6P in key brain areas indicated reconsolidation inhibition.MK‐801 given 24h before also increased glutamate receptors in a metaplastic fashion.‘Metaplastic’ MK‐801 might facilitated extinction… read more here.
Keywords: memory retrieval; instrumental memory; reconsolidation; nmda receptors ... See more keywords