LAUSR

Insulin Elevates ID2 Expression in Trophoblasts and Aggravates Preeclampsia in Obese ASB4-Null Mice

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2 Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24032149

Abstract: Obesity is a risk factor for preeclampsia. We investigated how obesity influences preeclampsia in mice lacking ankyrin-repeat-and-SOCS-box-containing-protein 4 (ASB4), which promotes trophoblast differentiation via degrading the inhibitor of DNA-binding protein 2 (ID2). Asb4−/− mice on… read more here.

Keywords: elevates id2; insulin elevates; like phenotypes; mice ... See more keywords