Specific deletion of CDC42 in pancreatic β cells attenuates glucose-induced insulin expression and secretion in mice
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DOI: 10.1016/j.mce.2020.111004
Abstract: Insulin is a key hormone for maintaining glucose homeostasis in organisms. In general, deficiency of insulin synthesis and secretion results in type I diabetes, whereas insulin resistance leads to type 2 diabetes. Cell division cycle… read more here.
Keywords: insulin; secretion; pancreatic cells; insulin expression ... See more keywords
Short‐term fasting promotes insulin expression in rat hypothalamus
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DOI: 10.1111/ejn.13607
Abstract: In the hypothalamus, insulin takes on many roles involved in energy homoeostasis. Therefore, the aim of this study was to examine hypothalamic insulin expression during the initial phase of the metabolic response to fasting. Hypothalamic… read more here.
Keywords: insulin; hypothalamus; term fasting; expression ... See more keywords
Centaurium erythraea extract reduces redox imbalance and improves insulin expression and secretion in pancreatic β-cells exposed to oxidative and nitrosative stress
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DOI: 10.2298/abs200127005d
Abstract: Paper description: Oxidative stress underlies b-cell damage and a diminished capacity for insulin secretion in diabetes. Previously we have shown that the Centaurium erythraea extract (CEe) exhibits a significant redox potential both in vitro and… read more here.
Keywords: cee; secretion; stress; insulin expression ... See more keywords