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Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300100
Abstract: Lipoic acid (LA) and dihydrolipoic acid (DHLA) are well established antioxidants to scavenge reactive oxygen species (ROS). However, they are carboxylates with ca. 4.7 pKa making them negatively charged at physiological pH (7.4) reducing their…
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Keywords:
enhanced neuroprotection;
polymers enhanced;
fibrillation;
insulin fibrillation ... See more keywords
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Published in 2020 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2020.01.042
Abstract: Abstract Insulin fibrillation poses a variety of problems in biomedical and biotechnological applications of insulin. Inhibiting insulin fibrillation is highly on demand to address those problems. We herein demonstrate the capability of amphiphilic sulfonatocalixarene to…
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Keywords:
fibrillation;
insulin fibrillation;
fibrillation amphiphilic;
amphiphilic sulfonatocalixarene ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021306
Abstract: Amyloidoses include a large variety of local and systemic diseases that share the common feature of protein unfolding or refolding into amyloid fibrils. The most studied amyloids are those directly involved in neurodegenerative diseases, while…
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Keywords:
inhibitors insulin;
peptide inhibitors;
fibrillation;
fibrillation current ... See more keywords