Articles with "insulin fibrillation" as a keyword



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Antioxidant Polymers with Enhanced Neuroprotection Against Insulin Fibrillation.

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Published in 2023 at "Macromolecular bioscience"

DOI: 10.1002/mabi.202300100

Abstract: Lipoic acid (LA) and dihydrolipoic acid (DHLA) are well established antioxidants to scavenge reactive oxygen species (ROS). However, they are carboxylates with ca. 4.7 pKa making them negatively charged at physiological pH (7.4) reducing their… read more here.

Keywords: enhanced neuroprotection; polymers enhanced; fibrillation; insulin fibrillation ... See more keywords
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Inhibition of insulin fibrillation by amphiphilic sulfonatocalixarene

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Published in 2020 at "Chinese Chemical Letters"

DOI: 10.1016/j.cclet.2020.01.042

Abstract: Abstract Insulin fibrillation poses a variety of problems in biomedical and biotechnological applications of insulin. Inhibiting insulin fibrillation is highly on demand to address those problems. We herein demonstrate the capability of amphiphilic sulfonatocalixarene to… read more here.

Keywords: fibrillation; insulin fibrillation; fibrillation amphiphilic; amphiphilic sulfonatocalixarene ... See more keywords
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Peptide Inhibitors of Insulin Fibrillation: Current and Future Challenges

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021306

Abstract: Amyloidoses include a large variety of local and systemic diseases that share the common feature of protein unfolding or refolding into amyloid fibrils. The most studied amyloids are those directly involved in neurodegenerative diseases, while… read more here.

Keywords: inhibitors insulin; peptide inhibitors; fibrillation; fibrillation current ... See more keywords