Caulerpa lentillifera inhibits protein-tyrosine phosphatase 1B and protects pancreatic beta cell via its insulin mimetic effect
Sign Up to like & getrecommendations! Published in 2017 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-017-0068-4
Abstract: The aim of this study was to determine whether Caulerpa lentillifea extract (CLE) can protect pancreatic beta cells and enhance insulin signaling in adipocytes. We measured the protein tyrosine phosphatase (PTP)-1B inhibitory effect of CLE… read more here.
Keywords: insulin; effect; pancreatic beta; cle ... See more keywords
Orally hypoglycemic activity of an insulin mimetic glycoprotein isolated from Cnidoscolus quercifolius Pohl. (Euphorbiaceae) seeds, Cq-IMP.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.05.033
Abstract: The genus Cnidoscolus (Euphorbiaceae) is widely distributed in tropical areas. In the Northeast of Brazil, the species C. quercifolius is endemic and has been used in traditional medicine. In this study, a novel protein was… read more here.
Keywords: protein; hypoglycemic activity; cnidoscolus quercifolius; insulin mimetic ... See more keywords
Oleanane Triterpenoids from the Leaves of Gymnema inodorum and Their Insulin Mimetic Activities.
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DOI: 10.1021/acs.jnatprod.0c00051
Abstract: During an effort to find insulin mimetic compounds, the leaves of Gymnema inodorum were shown to have a stimulatory effect on glucose uptake in 3T3-L1 adipocyte cells. Bioassay-guided fractionation on a 70% ethanol extract of… read more here.
Keywords: adipocyte cells; oleanane triterpenoids; insulin mimetic; gymnema inodorum ... See more keywords
Hydroxyoleoside-type seco-iridoids from Symplocos cochinchinensis and their insulin mimetic activity
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DOI: 10.1038/s41598-018-38013-4
Abstract: As part of an ongoing study of new insulin mimetic agents from medicinal plants, the 70% EtOH extract of Symplocos cochinchinensis was found to have a stimulatory effect on glucose uptake in 3T3-L1 adipocyte cells.… read more here.
Keywords: hydroxyoleoside type; type seco; insulin mimetic; symplocos cochinchinensis ... See more keywords
Glucocorticoid Receptor β Overexpression Has Agonist-Independent Insulin-Mimetic Effects on HepG2 Glucose Metabolism
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DOI: 10.3390/ijms23105582
Abstract: Glucocorticoids (GC) are steroids hormones that drive circulating glucose availability through gluconeogenesis in the liver. However, alternative splicing of the GR mRNA produces two isoforms, termed GRα and GRβ. GRα is the classic receptor that… read more here.
Keywords: independent insulin; overexpression; agonist independent; insulin mimetic ... See more keywords