A co-formulation of supramolecularly stabilized insulin and pramlintide enhances meal-time glucagon suppression in diabetic pigs
Sign Up to like & getrecommendations! Published in 2020 at "Nature biomedical engineering"
DOI: 10.1038/s41551-020-0555-4
Abstract: Treatment of patients with diabetes with insulin and pramlintide (an amylin analogue) is more effective than treatment with insulin only. However, because mixtures of insulin and pramlintide are unstable and have to be injected separately,… read more here.
Keywords: insulin; administration; suppression; glucagon ... See more keywords
A Novel Dual-Hormone Insulin-and-Pramlintide Artificial Pancreas for Type 1 Diabetes: A Randomized Controlled Crossover Trial
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DOI: 10.2337/dc19-1922
Abstract: OBJECTIVE The rapid insulin-alone artificial pancreas improves glycemia in type 1 diabetes but daytime control remains suboptimal. We propose two novel dual-hormone artificial pancreas systems. RESEARCH DESIGN AND METHODS We conducted a randomized crossover trial… read more here.
Keywords: insulin; insulin alone; artificial pancreas; insulin pramlintide ... See more keywords