Insulin regulates Bbs4 during adipogenesis
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DOI: 10.1002/iub.1626
Abstract: BardetâBiedl syndrome (BBS) is a pleiotropic autosomal recessive disorder associated with marked obesity, increased susceptibility to insulin resistance and type 2 diabetes. However, it is unknown whether the link between BBS and diabetes is indirect… read more here.
Keywords: insulin; bbs4 adipogenesis; bbs; regulates bbs4 ... See more keywords
Insulin regulates human mammosphere development and function
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DOI: 10.1007/s00441-020-03360-0
Abstract: Assessing the role of lactogenic hormones in human mammary gland development is limited due to issues accessing tissue samples and so development of a human in vitro three-dimensional mammosphere model with functions similar to secretory… read more here.
Keywords: insulin; regulates human; insulin regulates; human mammosphere ... See more keywords
Insulin Regulates Adrenal Steroidogenesis by Stabilizing SF-1 Activity
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DOI: 10.1038/s41598-018-23298-2
Abstract: Development of metabolic syndrome is associated with hyperactivity of the HPA axis characterized by elevated levels of circulating adrenal hormones including cortisol and aldosterone. However, the molecular mechanism leading to the dysregulation of the HPA… read more here.
Keywords: insulin; adrenal steroidogenesis; regulates adrenal; insulin regulates ... See more keywords
35-OR: Physiological Insulin Regulates Alternative mRNA Splicing in Liver and Muscle at Multiple Levels
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DOI: 10.2337/db19-35-or
Abstract: Alternative splicing of mRNAs contributes importantly to proteome diversity and tissue identity. Work by us and others have suggested that alternative splicing and the spliceosome are dysregulated in diabetes, but the role of this under… read more here.
Keywords: alternative splicing; insulin regulates; muscle; insulin ... See more keywords