Hepatic Phospholipid Remodeling Modulates Insulin Sensitivity and Systemic Metabolism.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300416
Abstract: The liver plays a central role in regulating glucose and lipid metabolism. Aberrant insulin action in the liver is a major driver of selective insulin resistance, in which insulin fails to suppress glucose production but… read more here.
Keywords: insulin resistance; metabolism; insulin sensitivity; insulin ... See more keywords
Glucocorticoid‐Induced Insulin Resistance in Men Is Associated With Suppressed Undercarboxylated Osteocalcin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3574
Abstract: In mice, glucocorticoid‐induced insulin resistance occurs largely through impaired osteoblast function and decreased circulating undercarboxylated osteocalcin (ucOC). Whether these mechanisms contribute to glucocorticoid‐induced insulin resistance in humans has yet to be established. In addition, the… read more here.
Keywords: glucocorticoid induced; insulin; insulin sensitivity; insulin resistance ... See more keywords
Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30179
Abstract: Exercise improves the insulin sensitivity of glucose uptake in skeletal muscle. Due to that, exercise has become a cornerstone treatment for type 2 diabetes mellitus (T2DM). The mechanisms by which exercise improves skeletal muscle insulin sensitivity… read more here.
Keywords: skeletal muscle; muscle; glucose uptake; insulin sensitivity ... See more keywords
Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution
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DOI: 10.1002/oby.23106
Abstract: Sex differences in insulin sensitivity are present throughout the life‐span, with men having a higher prevalence of insulin resistance and diabetes compared with women. Differences in lean mass, fat mass, and fat distribution—particularly ectopic fat—have… read more here.
Keywords: differences insulin; sex differences; sex; insulin sensitivity ... See more keywords
Branched‐chain amino acid supplementation impairs insulin sensitivity and promotes lipogenesis during exercise in diet‐induced obese mice
Sign Up to like & getrecommendations! Published in 2022 at "Obesity"
DOI: 10.1002/oby.23394
Abstract: Branched‐chain amino acids (BCAAs) are popular dietary supplements for exercise. However, increased BCAA levels positively correlate with obesity and diabetes. The metabolic impact of BCAA supplementation on insulin sensitivity during exercise is less understood. read more here.
Keywords: supplementation; chain amino; insulin sensitivity; branched chain ... See more keywords
Effect of sleep restriction on insulin sensitivity and energy metabolism in postmenopausal women: A randomized crossover trial
Sign Up to like & getrecommendations! Published in 2023 at "Obesity"
DOI: 10.1002/oby.23739
Abstract: The aim of this study was to investigate the effect of sleep restriction (SR) on insulin sensitivity and energy metabolism in postmenopausal women. read more here.
Keywords: sleep restriction; energy metabolism; effect sleep; restriction insulin ... See more keywords
The effect of dietary pioglitazone supplementation on milk yield, insulin sensitivity and GH–IGF‐I axis in Holstein dairy cows during the transition period
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.1018
Abstract: Abstract Background High‐yielding dairy cows develop insulin resistance during late gestation associated with disruption of the growth hormone (GH)–insulin‐like growth factor (IGF)‐I axis and cause metabolic and reproductive disorders. Objective This study aimed to determine… read more here.
Keywords: supplementation; dairy cows; igf axis; insulin sensitivity ... See more keywords
Trajectories of glycaemia, insulin sensitivity and insulin secretion in South Asian and white individuals before diagnosis of type 2 diabetes: a longitudinal analysis from the Whitehall II cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4275-6
Abstract: Aims/hypothesisSouth Asian individuals have reduced insulin sensitivity and increased risk of type 2 diabetes compared with white individuals. Temporal changes in glycaemic traits during middle age suggest that impaired insulin secretion is a particular feature… read more here.
Keywords: white individuals; south asian; insulin sensitivity; diagnosis ... See more keywords
Differential effects of age and sex on insulin sensitivity and body composition in adolescent offspring of women with type 1 diabetes: results from the EPICOM study
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4458-1
Abstract: Aims/hypothesisThe aim of this study was to investigate the influence of age and sex on insulin sensitivity and insulin secretion in the adolescent offspring of women with type 1 diabetes, compared with the background population.MethodsThis… read more here.
Keywords: age; index; offspring women; insulin sensitivity ... See more keywords
Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05296-0
Abstract: Aims/hypothesis Obesity and insulin resistance may be associated with elevated plasma concentration of branched-chain amino acids (BCAAs) and impaired BCAA metabolism. However, it is unknown whether the insulin-sensitising effect of long-term exercise can be explained… read more here.
Keywords: insulin; metabolism; normoglycaemic men; insulin sensitivity ... See more keywords
Short-term, but not acute, intake of New Zealand blackcurrant extract improves insulin sensitivity and free-living postprandial glucose excursions in individuals with overweight or obesity
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nutrition"
DOI: 10.1007/s00394-020-02329-7
Abstract: Abstract Impaired postprandial glucose handling and low-grade systemic inflammation are risk factors for developing insulin resistance in individuals with overweight or obesity. Acute ingestion of anthocyanins improves postprandial glucose responses to a single carbohydrate-rich meal… read more here.
Keywords: free living; postprandial glucose; insulin sensitivity; nzbc extract ... See more keywords