Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression.
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DOI: 10.1172/jci.insight.93098
Abstract: Advanced cancer induces fundamental changes in metabolism and promotes cardiac atrophy and heart failure. We discovered systemic insulin deficiency in cachectic cancer patients. Similarly, mice with advanced B16F10 melanoma (B16F10-TM) or colon 26 carcinoma (C26-TM)… read more here.
Keywords: insulin; insulin supplementation; systemic insulin; cancer ... See more keywords