Dityrosine administration induces dysfunction of insulin secretion accompanied by diminished thyroid hormones T3 function in pancreas of mice
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DOI: 10.1007/s00726-017-2442-1
Abstract: Oxidized tyrosine products are commonly found in food with high protein content and have been demonstrated to cause damage of liver and kidney in our previous studies. Dityrosine (Dityr) is a typical oxidized tyrosine product.… read more here.
Keywords: dityr; insulin synthesis; thyroid hormones; function pancreas ... See more keywords
miR-149 Negative Regulation of mafA Is Involved in the Arsenite-Induced Dysfunction of Insulin Synthesis and Secretion in Pancreatic Beta Cells
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DOI: 10.1093/toxsci/kfy150
Abstract: Chronic exposure to arsenic, a potent environmental oxidative stressor, is associated with the incidence of diabetes. However, the mechanisms for arsenite-induced reduction of insulin remain largely unclear. After CD1 mice were treated with 20 or… read more here.
Keywords: insulin; mir 149; synthesis secretion; insulin synthesis ... See more keywords