Insulin therapy for glycaemic control in critically ill children
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DOI: 10.1002/14651858.cd009983.pub2
Abstract: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Our primary objective is to assess the effects of maintaining stricter glycaemic control using intensive insulin therapy versus conventional insulin therapy… read more here.
Keywords: paediatric intensive; intensive care; insulin therapy; care patients ... See more keywords
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy
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DOI: 10.1002/2211-5463.13556
Abstract: Insulin therapy, pancreas transplantation and β cell regeneration are among the suggested treatment strategies for type 1 diabetes. It has been shown that some antimicrobial peptides have the potential to increase insulin release and to… read more here.
Keywords: cell; insulin therapy; cell regeneration; treatment ... See more keywords
Intensive insulin therapy combined with metformin is associated with reduction in both glucose variability and nocturnal hypoglycaemia in patients with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2913
Abstract: The effect on glucose variability in patients with intensive insulin therapy has not been fully understood. This observational study investigated the different glucose variability and hypoglycaemia patterns in type 2 diabetes patients treated with continuous… read more here.
Keywords: intensive insulin; insulin therapy; variability; glucose variability ... See more keywords
Improvement in Hyperglycemia Prevents Surgical Site Infection Irrespective of Insulin Therapy in Non-diabetic Patients Undergoing Gastrointestinal Surgery
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DOI: 10.1007/s00268-020-05371-y
Abstract: Background Intensive glycemic control is recommended to prevent surgical site infections (SSI). Our aim was to evaluate retrospectively the effect of improvement in hyperglycemia irrespective of insulin use on the incidence of SSI in non-diabetic… read more here.
Keywords: surgery; insulin therapy; diabetic patients; hyperglycemia ... See more keywords
Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high-fat-diet-treated mice
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DOI: 10.1007/s00592-019-01436-0
Abstract: Aims Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its… read more here.
Keywords: effects intensive; intensive insulin; insulin therapy; gut microbiota ... See more keywords
Cardiovascular Safety of Antidiabetic Drugs in the Hospital Setting
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DOI: 10.1007/s11892-017-0884-1
Abstract: Purpose of ReviewPatients with diabetes and/or stress hyperglycemia requires good glycemic control in the hospital setting, often requiring the use of glucose-lowering therapy. Standard-of-care dictates that non-insulin therapy be discontinued, with insulin therapy initiated using… read more here.
Keywords: antidiabetic drugs; safety; insulin therapy; cardiovascular safety ... See more keywords
Once-Weekly Dulaglutide with Insulin Therapy for Type 2 Diabetes: Efficacy and Safety Results from a Phase 4, Randomized, Placebo-Controlled Study
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DOI: 10.1007/s13300-019-00726-8
Abstract: Introduction Although global studies have investigated the combination of dulaglutide with insulin in patients with type 2 diabetes mellitus (T2DM), differences in lean body mass and dulaglutide dosing can complicate the extrapolation of global study… read more here.
Keywords: placebo; insulin; insulin therapy; weekly dulaglutide ... See more keywords
IDegLira Improves Glycemic Control in Japanese Patients with Uncontrolled Type 2 Diabetes on Premixed Insulin Therapy
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DOI: 10.1007/s13300-019-00730-y
Abstract: Introduction DUAL II Japan (NCT02911948) was a 26-week, phase 3a randomized, treat-to-target trial which compared the efficacy and safety of IDegLira with degludec in 210 Japanese patients with type 2 diabetes (T2D) uncontrolled on premixed or basal insulin… read more here.
Keywords: insulin; trial; insulin therapy; premixed insulin ... See more keywords
Clinical features of cases of seroconversion of anti-glutamic acid decarboxylase antibody during the clinical course of type 2 diabetes: a nationwide survey in Japan
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DOI: 10.1007/s13340-017-0312-4
Abstract: The pathogenesis of type 1 diabetes is different from that of type 2 diabetes, and anti-glutamic acid decarboxylase antibody (GADA) helps to diagnose autoimmune type 1 diabetes. Some studies reported that GADA seroconversion occurs during… read more here.
Keywords: type; type diabetes; insulin therapy; gada seroconversion ... See more keywords
Psychological reluctance to insulin therapy: as an illness side of diabetes mellitus
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DOI: 10.1007/s13340-018-0349-z
Abstract: In the earlier stages of type 2 diabetes mellitus, the disease can be managed with lifestyle modification with or without oral anti-diabetic drugs (OADs). However, because of the progressive nature of the disease caused by… read more here.
Keywords: insulin; initiation; insulin therapy; disease ... See more keywords
Enhancing Resources for Healthcare Professionals Caring for People on Intensive Insulin Therapy: Summary from a National Workshop.
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DOI: 10.1016/j.diabres.2020.108169
Abstract: In June 2019, the Leona M. and Harry B. Helmsley Charitable Trust and JDRF International (JDRF) co-sponsored the Healthcare Professional Resource Workshop in San Francisco, California. The workshop convened stakeholders in the diabetes field in… read more here.
Keywords: workshop; intensive insulin; caring people; insulin therapy ... See more keywords