Intranasal insulin treatment restores cognitive deficits and insulin signaling impairment induced by repeated methamphetamine exposure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26398
Abstract: Long‐term use of methamphetamine (MA) causes a broad range of cognitive deficits. Recently, it has been reported insulin signaling and mitochondrial biogenesis are involved in cognitive processes. This study aimed to examine whether MA induces… read more here.
Keywords: insulin; cognitive deficits; signaling impairment; insulin treatment ... See more keywords
Intranasal Insulin Treatment Attenuates Metabolic Distress and Early Brain Injury After Subarachnoid Hemorrhage in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Neurocritical Care"
DOI: 10.1007/s12028-020-01011-4
Abstract: Background Intranasal administration of insulin to the brain bypasses the blood brain barrier (BBB) and can increase cerebral glucose uptake and prevent energy failure. Intranasal insulin treatment has shown neuroprotective effects in multiple central nervous… read more here.
Keywords: brain; insulin treatment; intranasal insulin; sah ... See more keywords
Psychometric Analysis Regarding the Barriers to Providing Effective Insulin Treatment in Type 2 Diabetic Patients
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes Therapy"
DOI: 10.1007/s13300-020-00947-2
Abstract: Introduction A psychometric analysis on type 2 diabetic (T2D) patients was performed to assess whether glycated hemoglobin (HbA1c) levels were dependent upon either the psychologic or economic attitude toward the use of insulin as a… read more here.
Keywords: insulin; psychometric analysis; insulin treatment; hba1c ... See more keywords
All-cause mortality and cardiovascular safety of basal insulin treatment in patients with type 2 diabetes mellitus: a systematic review with meta-analysis and trial sequential analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2021.108688
Abstract: AIM To evaluate the risk of all-cause and cardiovascular mortality, acute myocardial infarction, and stroke associated with insulin treatment in patients with type 2 diabetes. METHODS A systematic review with meta-analysis of randomized clinical trials… read more here.
Keywords: analysis; treatment; insulin treatment; mortality ... See more keywords
Intranasal insulin treatment alleviates methamphetamine induced anxiety-like behavior and neuroinflammation
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.09.026
Abstract: Insulin, as a peptide hormone, has recently gained attention for its pro-cognitive, anti-inflammatory and neuroprotective effects in the central nervous system (CNS). Most studies have indicated anxiogenic and neuroinflammatory effects of methamphetamine (MA) and other… read more here.
Keywords: treatment; insulin treatment; like behavior; anxiety like ... See more keywords
Effect of systemic insulin treatment on diabetic wound healing
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DOI: 10.1111/wrr.12514
Abstract: This study investigates if different diabetic treatment regimens affect diabetic foot ulcer healing. From January 2013 to December 2014, 107 diabetic foot ulcers in 85 patients were followed until wound healing, amputation or development of… read more here.
Keywords: wound healing; systemic insulin; treatment; wound ... See more keywords
Five-Year Predictors of Insulin Initiation in People with Type 2 Diabetes under Real-Life Conditions
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes Research"
DOI: 10.1155/2018/7153087
Abstract: We performed a real-life analysis of clinical and laboratory parameters, in orally treated T2DM patients aiming at identifying predictors of insulin treatment initiation. Overall, 366955 patients (55.8% males, age 65 ± 11 years, diabetes duration 7 ± 8 years)… read more here.
Keywords: predictors insulin; initiation; treatment; insulin treatment ... See more keywords
Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes Research"
DOI: 10.1155/2020/9626398
Abstract: Introduction Current clinical guidelines for management of diabetic peripheral neuropathy (DPN) emphasize good glycemic control. However, this has limited effect on prevention of DPN in type 2 diabetic (T2D) patients. This study investigates the effect… read more here.
Keywords: nerve; treatment; insulin treatment; nerve fiber ... See more keywords
The effects of exercise training versus intensive insulin treatment on skeletal muscle fibre content in type 1 diabetes mellitus rodents
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DOI: 10.1186/s12944-021-01494-w
Abstract: Background Intensive-insulin treatment (IIT) strategy for patients with type 1 diabetes mellitus (T1DM) has been associated with sedentary behaviour and the development of insulin resistance. Exercising patients with T1DM often utilize a conventional insulin treatment… read more here.
Keywords: insulin; muscle; insulin treatment; content ... See more keywords
Prediction of insulin therapy in women with gestational diabetes: a systematic review and meta-analysis of observational studies
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2021-0247
Abstract: Abstract Objectives To identify antenatal risk factors that may predict the need for insulin treatment upon diagnosis of gestational diabetes (GDM), that is, to identify the specific characteristics of women diagnosed with GDM who did… read more here.
Keywords: review meta; insulin treatment; systematic review; gestational diabetes ... See more keywords
Intranasal Insulin Prevents Anesthesia-induced Cognitive Impairments in Aged Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Current Alzheimer research"
DOI: 10.2174/1567205015666181031145045
Abstract: BACKGROUND Preclinical and clinical evidence suggests that elderly individuals are at increased risk of cognitive decline after general anesthesia. General anesthesia is also believed to be a risk factor for Postoperative Cognitive Dysfunction (POCD) and… read more here.
Keywords: insulin; anesthesia induced; insulin treatment; intranasal insulin ... See more keywords