Zwitterionic hydrophilic interaction liquid chromatography-tandem mass spectrometry with HybridSPE-precipitation for the determination of intact cisplatin in human plasma.
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DOI: 10.1016/j.talanta.2017.06.002
Abstract: Cisplatin is a first-line chemotherapeutic for the treatment of a wide variety of cancers since its discovery in the 1960s. Although various techniques have been reported for the measurement of total platinum in biological matrices,… read more here.
Keywords: plasma; determination intact; mass spectrometry; precipitation ... See more keywords