Optimization of Higher-Energy Collisional Dissociation Fragmentation Energy for Intact Protein-Level Tandem Mass Tag Labeling.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00549
Abstract: Isobaric chemical tag labeling (e.g., TMT) is a commonly used approach in quantitative proteomics, and quantification is enabled through detection of low-mass reporter ions generated after MS2 fragmentation. Recently, we have introduced and optimized an… read more here.
Keywords: intact protein; fragmentation; energy; tag labeling ... See more keywords
High-Throughput Deconvolution of Intact Protein Mass Spectra for the Screening of Covalent Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00273
Abstract: Deconvolution from intact protein mass-to-charge spectra to mass spectra is essential to generate interpretable data for mass spectrometry (MS) platforms coupled to ionization sources that produce multiply charged species. Infrared matrix-assisted laser desorption electrospray ionization… read more here.
Keywords: intact protein; protein mass; deconvolution; mass spectra ... See more keywords
Ultrahigh-Throughput Intact Protein Analysis with Acoustic Ejection Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00276
Abstract: The need for high-throughput intact protein analysis has been rising as drug discovery increasingly requires the analysis of large sets of covalent modifiers and protein therapeutics. Liquid chromatography-mass spectrometry (LC-MS) is the primary analytical tool… read more here.
Keywords: throughput intact; intact protein; mass spectrometry; protein analysis ... See more keywords
Shorter Time to Full Preterm Feeding Using Intact Protein Formula: A Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph16162911
Abstract: Background: This study was carried out to evaluate enteral feeding advancement and tolerance in preterm infants receiving one of two marketed formulas: intact protein preterm formula (IPF) or extensively hydrolyzed formula (EHF) for the first… read more here.
Keywords: formula; preterm; time; study ... See more keywords