Identification of MEG8/miR‐378d/SOBP axis as a novel regulatory network and associated with immune infiltrates in ovarian carcinoma by integrated bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3854
Abstract: To investigate the potential molecular mechanism of ovarian cancer (OC) evolution and immunological correlation using the integrated bioinformatics analysis. read more here.
Keywords: mir 378d; integrated bioinformatics; bioinformatics analysis; identification meg8 ... See more keywords
Integrated bioinformatics analysis of the anti-atherosclerotic mechanisms of the polysaccharide CM1 from Cordyceps militaris.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.10.175
Abstract: Cordyceps militaris is a well-known traditional Chinese medicine. Studies have demonstrated that the polysaccharides of C. militaris have various bioactivities. However, their mechanisms of action remain unclear. We previously purified a water-soluble polysaccharide CM1 from… read more here.
Keywords: cm1; cordyceps militaris; analysis; integrated bioinformatics ... See more keywords
Identification and validation of a miRNA-based prognostic signature for cervical cancer through an integrated bioinformatics approach
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-79337-4
Abstract: Cervical cancer is the fourth most common cancer in women worldwide. Increasing evidence has shown that miRNAs are related to the progression of cervical cancer. However, the mechanisms that affect the prognosis of cancer are… read more here.
Keywords: identification validation; bioinformatics approach; cervical cancer; integrated bioinformatics ... See more keywords
Prognostic value of gastric cancer‐associated gene signatures: Evidence based on a meta‐analysis using integrated bioinformatics methods
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13823
Abstract: Abstract Selecting differentially expressed genes (DEGs) based on integrated bioinformatics analyses has been used in previous studies to explore potential biomarkers in gastric cancer (GC) with microarray and RNA sequencing data. However, the genes obtained… read more here.
Keywords: bioinformatics methods; gastric cancer; prognostic value; value ... See more keywords
Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s152238
Abstract: Background The mortality rate associated with ovarian cancer ranks the highest among gynecological malignancies. However, the cause and underlying molecular events of ovarian cancer are not clear. Here, we applied integrated bioinformatics to identify key… read more here.
Keywords: analysis; integrated bioinformatics; ovarian cancer; expressed genes ... See more keywords
Identification of Drug Targets and Agents Associated with Hepatocellular Carcinoma through Integrated Bioinformatics Analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Current cancer drug targets"
DOI: 10.2174/1568009623666230214100159
Abstract: BACKGROUND Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death globally. The mechanisms underlying the development of HCC are mostly unknown till now. OBJECTIVE The main goal of this study was to identify… read more here.
Keywords: hub cdegs; hepatocellular carcinoma; integrated bioinformatics; drug ... See more keywords
Identification of Heparan Sulfate in Dilated Cardiomyopathy by Integrated Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.900428
Abstract: Objectives Heparan sulfate (HS) forms heparan sulfate proteoglycans (HSPGs), such as syndecans (SDCs) and glypicans (GPCs), to perform biological processes in the mammals. This study aimed to explore the role of HS in dilated cardiomyopathy… read more here.
Keywords: heparan sulfate; identification; analysis; integrated bioinformatics ... See more keywords
Identifying key genes in CD4+ T cells of systemic lupus erythematosus by integrated bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.941221
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by excessive activation of T and B lymphocytes and breakdown of immune tolerance to autoantigens. Despite several mechanisms including the genetic alterations and inflammatory responses… read more here.
Keywords: cd4 cells; genes cd4; systemic lupus; analysis ... See more keywords
Integrated bioinformatics analysis identifies shared immune changes between ischemic stroke and COVID 19
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1102281
Abstract: Although COVID-19 is primarily a respiratory disease, its neurological complications, such as ischemic stroke (IS), have aroused growing concerns and reports. However, the molecular mechanisms that underlie IS and COVID-19 are not well understood. Therefore,… read more here.
Keywords: covid; integrated bioinformatics; ischemic stroke; bioinformatics analysis ... See more keywords
Integrated bioinformatics analysis uncovers characteristic genes and molecular subtyping system for endometriosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.932526
Abstract: Objective: Endometriosis is a chronic inflammatory estrogen-dependent disease with the growth of endometrial tissues outside the uterine cavity. Nevertheless, the etiology of endometriosis is still unclear. Integrated bioinformatics analysis was implemented to reveal the molecular… read more here.
Keywords: endometriosis; bioinformatics analysis; analysis; integrated bioinformatics ... See more keywords
Exploring the common diagnostic gene KCNJ15 and shared pathway of ankylosing spondylitis and ulcerative colitis through integrated bioinformatics
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1146538
Abstract: Introduction: The similarity between ankylosing spondylitis (AS) and ulcerative colitis (UC) in incidence rate and pathogenesis has been revealed. But the common pathogenesis that explains the relationship between AS and UC is still lacked, and… read more here.
Keywords: diagnostic gene; expression; integrated bioinformatics; common diagnostic ... See more keywords