The integrated biomarker response: a suitable tool to evaluate toxicity of metal-based nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Nanotoxicology"
DOI: 10.1080/17435390.2016.1269374
Abstract: Abstract Nanotechnology is a much promising field of science and technology with applications in a wide range of areas such as electronics, biomedical applications, energy and cosmetics. Metal-based engineered nanoparticles (ENPs) are common in many… read more here.
Keywords: integrated biomarker; response; metal; metal based ... See more keywords
An integrated biomarker of PD‐L1 expression and intraepithelial CD8 + T cell infiltration was associated with the prognosis of lung cancer patients after intracranial resection of brain metastases
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14473
Abstract: Brain metastases (BM) are common in lung cancer. However, data on the status of immune biomarkers in BM lesions remain limited. read more here.
Keywords: lung cancer; brain metastases; cancer; integrated biomarker ... See more keywords
Integrated biomarker profiling of smokers with periodontitis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Periodontology"
DOI: 10.1111/jcpe.12659
Abstract: BACKGROUND In the context of precision medicine, understanding patient-specific variation is an important step in developing targeted and patient-tailored treatment regimens for periodontitis. While several studies have successfully demonstrated the usefulness of molecular expression profiling… read more here.
Keywords: integrated biomarker; patient specific; sva svm; disease ... See more keywords
Abstract A15: Integrated biomarker trials to evaluate myeloid and lymphoid composition of HNSCC and solid tumors treated with pepinemab and combinations with checkpoint inhibitors
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.aacrahns19-a15
Abstract: Recruitment of immunosuppressive myeloid cells into the tumor microenvironment (TME) is a critical limitation to the efficacy of immune checkpoint inhibitors (ICIs) in patients with head and neck squamous cell carcinoma (HNSCC). In preclinical models,… read more here.
Keywords: integrated biomarker; checkpoint inhibitors; biomarker; antibody ... See more keywords
Pilot integrated biomarker study of VX15/2503 in combination with ipilimumab and/or nivolumab in patients with resectable metastatic melanoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.tps9603
Abstract: TPS9603 Background: Interrogation of the tumor microenvironment (TME) is crucial to provide insight into biological activity, resistance mechanisms and implementation of rational combination immunotherapies. Semaphorin 4D (SEMA4D, CD100) has broad immunomodulatory effects in the TME.… read more here.
Keywords: biomarker; combination; melanoma; vx15 2503 ... See more keywords
Integrated biomarker response in signal crayfish Pacifastacus leniusculus exposed to diphenhydramine.
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.2139/ssrn.4176680
Abstract: Diphenhydramine (DPH) is a pharmaceutical with multiple modes of action, primarily designed as an antihistamine therapeutic drug. Among antihistamines, DPH is a significant contaminant in the environment, frequently detected in surface waters, sediments, and tissues… read more here.
Keywords: pacifastacus leniusculus; biomarker response; integrated biomarker; crayfish pacifastacus ... See more keywords