An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.03.052
Abstract: Resistance to chemotherapy plays a significant role in cancer mortality. To identify genetic units affecting sensitivity to cytarabine, the mainstay of treatment for acute myeloid leukemia (AML), we developed a comprehensive and integrated genome-wide platform based on… read more here.
Keywords: genome wide; non coding; wide crispra; resistance ... See more keywords
Integrated Genome Browser App Store
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac109
Abstract: Abstract Summary Rapid progress in genome science requires equally rapid visualization software development so that researchers can better explore and understand novel datasets. To make developing new visualizations faster and easier, we previously re-factored the… read more here.
Keywords: store; integrated genome; app store; igb ... See more keywords
iGDP: an integrated Genome Decontamination Pipeline for wild ciliated microeukaryotes.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology resources"
DOI: 10.1111/1755-0998.13782
Abstract: Ciliates are a large group of ubiquitous and highly diverse single‐celled eukaryotes that play an essential role in the functioning of microbial food webs. However, their genomic diversity is far from clear due to the… read more here.
Keywords: decontamination pipeline; ecology; igdp; integrated genome ... See more keywords