An integrated metabolomics and proteogenomics approach reveals molecular alterations following carbamazepine exposure in the male mussel Mytilus galloprovincialis.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2021.131793
Abstract: Carbamazepine is one of the most abundant pharmaceutical active compounds detected in aquatic systems. Based on laboratory exposures, carbamazepine has been proven to adversely affect aquatic organisms. However, the underlying molecular events remain poorly understood.… read more here.
Keywords: mytilus galloprovincialis; carbamazepine; integrated metabolomics; proteogenomics approach ... See more keywords
Integrated Metabolomics and Transcriptomics Analyses Reveal Metabolic Mechanisms in Porcine Intestinal Epithelial Cells under Zearalenone Stress.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01107
Abstract: Zearalenone (ZEA) is a mycotoxin that frequently occurs in agricultural crops and related products and seriously threatens both animal feed and human food safety. To identify key metabolites and regulators involved in ZEA toxicological processes,… read more here.
Keywords: metabolism; zea; integrated metabolomics; zea exposure ... See more keywords
Integrated Metabolomics and Lipidomics Approach for the Study of Metabolic Network and Early Diagnosis in Cerebral Infarction.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00348
Abstract: Cerebral infarction (CI) remains a major cause of high mortality and long-term disability worldwide. The exploration of biomarkers and pathogenesis is crucial for the early diagnosis of CI. Although the understanding of metabolic perturbations underlying… read more here.
Keywords: metabolic network; integrated metabolomics; metabolomics lipidomics; cerebral infarction ... See more keywords
Integrated metabolomics and lipidomics reveal fatty acid dysregulation in aortic dissection independent of hypertension
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-23667-8
Abstract: Aortic dissection (AD), characterized by rupture of the aortic wall, presents significant diagnostic challenges due to its rapid onset and nonspecific clinical symptoms. Although conventional imaging techniques are clinically useful, they typically lack sensitivity for… read more here.
Keywords: aortic dissection; metabolomics lipidomics; integrated metabolomics; lipidomics reveal ... See more keywords
Integrated Metabolomics and Transcriptome Analysis of Flavonoid Biosynthesis in Safflower (Carthamus tinctorius L.) With Different Colors
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.712038
Abstract: Safflower is widely used in dying and in traditional medicine, and C-glucosylquinochalcones are the main metabolic species in the red color of safflower. Various safflower cultivars have flowers with different colors. However, the metabolic and… read more here.
Keywords: biosynthesis; safflower; integrated metabolomics; analysis ... See more keywords
Integrated metabolomics and proteomics analysis reveals the accumulation mechanism of bioactive components in Polygonatum odoratum
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2024.1487613
Abstract: Polygonatum odoratum (Mill.) Druce is rich in bioactive components with high medicinal value. To maximize the clinical benefits, it is of great significance to efficiently extract key bioactive components from appropriate growth stages in which… read more here.
Keywords: polygonatum odoratum; accumulation; bioactive components; metabolomics proteomics ... See more keywords