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Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer

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0 Published in 2018 at "Cell Metabolism"

DOI: 10.1016/j.cmet.2018.08.021

Abstract: Summary Late-phase clinical trials investigating metformin as a cancer therapy are underway. However, there remains controversy as to the mode of action of metformin in tumors at clinical doses. We conducted a clinical study integrating… read more here.

Keywords: pharmacodynamic analysis; integrated pharmacodynamic; metformin; breast cancer ... See more keywords