Chemical Approach to Biological Safety: Molecular‐Level Control of an Integrated Zinc Finger Nuclease
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DOI: 10.1002/cbic.201700420
Abstract: Application of artificial nucleases (ANs) in genome editing is still hindered by their cytotoxicity related to off‐target cleavages. This problem can be targeted by regulation of the nuclease domain. Here, we provide an experimental survey… read more here.
Keywords: zinc finger; nuclease; integrated zinc; approach ... See more keywords