Integrating external controls in case–control studies improves power for rare‐variant tests
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DOI: 10.1002/gepi.22444
Abstract: Large‐scale sequencing and genotyping data provide an opportunity to integrate external samples as controls to improve power of association tests. However, due to the systematic differences between genotyped samples from different studies, naively aggregating the… read more here.
Keywords: rare variant; power; external controls; variant ... See more keywords