Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/0008-5472.can-20-1231
Abstract: This study identifies the double-edged sword of high ploidy as a prerequisite to personalize combination therapies with cytotoxic drugs and inhibitors of signal transduction pathways such as MTOR-Is. Breast cancer progresses in a multistep process… read more here.
Keywords: mathematical modeling; integrating mathematical; invasion; modeling high ... See more keywords