Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging.
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DOI: 10.1021/acs.analchem.2c01537
Abstract: A newly synthesized proteome reflects perturbations sensitively and maintains homeostasis in cells. To investigate the low abundant newly synthesized proteins (NSPs) from a complex background proteome, an enrichment process with high selectivity and reliability is… read more here.
Keywords: synthesized proteins; integrating tandem; tandem orthogonal; strategy ... See more keywords