Integration of hypoxic HIF-α signaling in blood cancers
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DOI: 10.1038/onc.2017.119
Abstract: Hypoxia (low O2) is a fundamental microenvironmental determinant of bone marrow (BM) pathophysiology. Recent data from molecular and clinical studies indicate that hematopoiesis and leukemogenesis are dependent upon hypoxia-inducible factors (HIFs), a family of essential… read more here.
Keywords: hif signaling; integration hypoxic; hypoxic hif; blood ... See more keywords