CRISPR-Mediated Integration of Large Gene Cassettes Using AAV Donor Vectors.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.06.064
Abstract: The CRISPR/Cas9 system has recently been shown to facilitate high levels of precise genome editing using adeno-associated viral (AAV) vectors to serve as donor template DNA during homologous recombination (HR). However, the maximum AAV packaging capacity… read more here.
Keywords: genome editing; integration; crispr mediated; donor ... See more keywords
Integration of Large-Scale Genomic Data Sources With Evolutionary History Reveals Novel Genetic Loci for Congenital Heart Disease
Sign Up to like & getrecommendations! Published in 2019 at "Circulation. Genomic and Precision Medicine"
DOI: 10.1161/circgen.119.002694
Abstract: Supplemental Digital Content is available in the text. read more here.
Keywords: scale genomic; genomic data; large scale; sources evolutionary ... See more keywords