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Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26423
Abstract: Glycine encephalopathy, also known as nonketotic hyperglycinemia (NKH), is an inherited neurometabolic disorder with variable clinical course and severity, ranging from infantile epileptic encephalopathy to psychiatric disorders. A precise phenotypic characterization and an evaluation of…
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Keywords:
nonketotic hyperglycinemia;
integrative approach;
approach predict;
predict severity ... See more keywords
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Published in 2020 at "Journal of Behavioral Decision Making"
DOI: 10.1002/bdm.2175
Abstract: Decisions vary. They vary in both content and complexity. People also vary. An important way that people vary is how much they think about a decision. Some prior research investigating thinking and decision making largely…
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Keywords:
person;
decisions integrative;
decision making;
decision ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8618-7_8
Abstract: Since cell regulation and protein expression can be dramatically altered upon infection by viruses, studying the mechanisms by which viruses infect cells and the regulatory networks they disrupt is essential to understanding viral pathogenicity. This…
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Keywords:
protein;
integrative approach;
biology;
virus host ... See more keywords
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Published in 2021 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2021.02.001
Abstract: APOE (apolipoprotein E) is a key regulator of lipid metabolism and a leading genetic risk factor for Alzheimer's disease. While APOE participates in multiple biological pathways, its roles in diseases are largely due to the…
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Keywords:
targeting apoe;
integrative approach;
intervention;
disease ... See more keywords
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Published in 2019 at "Journal of Cleaner Production"
DOI: 10.1016/j.jclepro.2018.09.187
Abstract: Abstract The aim of this paper is to present a new, integrative approach for calculating Fate Factors (FF) for nanomaterials by combining the USEtox2.0 modelling framework with SimpleBox4Nano (SB4N), an advanced environmental fate model for…
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Keywords:
towards usetox4nano;
nano tio2;
fate;
approach ... See more keywords
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Published in 2017 at "Molecular phylogenetics and evolution"
DOI: 10.1016/j.ympev.2017.07.024
Abstract: Although extensive research has been carried out on the desert ants in the genus Cataglyphis in recent years, some of the specific intra- and interspecific relationships remain elusive. The present study disentangles the phylogenetic relationships…
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Keywords:
complex israel;
species delimitation;
integrative approach;
bicolor ... See more keywords
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Published in 2017 at "Behavioral and Brain Sciences"
DOI: 10.1017/s0140525x17000619
Abstract: Abstract In response to the commentaries, we have refined our suggested model and discussed ways in which the model could be further expanded. In this context, we have elaborated on the role of specific continuous…
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Keywords:
approach numerical;
numerical cognition;
integrative approach;
toward integrative ... See more keywords
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Published in 2017 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.6b01185
Abstract: An integrative approach combining traditional natural products chemistry, molecular networking, and mass spectrometry imaging has been undertaken to decipher the molecular dialogue between the fungus Paraconiothyrium variabile and the bacterium Bacillus subtilis, which were isolated…
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Keywords:
integrative approach;
bacillus subtilis;
approach decipher;
paraconiothyrium variabile ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10357-3
Abstract: Numerical model-based simulations provide important insights into ion channel gating when experimental limitations exist. Here, a novel strategy combining numerical simulations with patch clamp experiments was used to investigate the net positive charges in the…
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Keywords:
voltage;
approach electrophysiological;
integrative approach;
pkd2l1 channel ... See more keywords
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Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25086-4
Abstract: Zoantharians represent a group of marine invertebrates widely distributed from shallow waters to the deep sea. Despite a high diversity and abundance in the rocky reefs of the Pacific Ocean, very few studies have been…
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Keywords:
diversity;
tropical eastern;
integrative approach;
zoantharian diversity ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-00682-z
Abstract: Small ruminants are suited to a wide variety of habitats and thus represent promising study models for identifying genes underlying adaptations. Here, we considered local Mediterranean breeds of goats (n = 17) and sheep (n = 25) from Italy,…
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Keywords:
local adaptations;
mediterranean sheep;
adaptations mediterranean;
goats integrative ... See more keywords