Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain.
Sign Up to like & getrecommendations! Published in 2022 at "GeroScience"
DOI: 10.1007/s11357-022-00537-z
Abstract: Intermittent fasting (IF) remains the most effective intervention to achieve robust anti-aging effects and attenuation of age-related diseases in various species. Epigenetic modifications mediate the biological effects of several environmental factors on gene expression; however,… read more here.
Keywords: intermittent fasting; epigenomic transcriptomic; transcriptomic analyses; integrative epigenomic ... See more keywords
An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1‐positive neuroendocrine carcinoma
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DOI: 10.1111/cas.15764
Abstract: Neuroendocrine carcinoma (NEC) is a highly aggressive subtype of the neuroendocrine tumor with an extremely poor prognosis. We have previously conducted a comprehensive genomic analysis of over 100 cases of NEC of the gastrointestinal system… read more here.
Keywords: epigenomic approach; gis nec; elf3 oncogenic; neuroendocrine carcinoma ... See more keywords
Abstract 14308: Integrative Epigenomic Analysis Identifies Enhancer Modifying Variants Linked to Cardiomyopathy Genes
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.14308
Abstract: Introduction: Inherited cardiomyopathy is caused by mutations in more than 100 genes. A well-recognized clinical feature of genetic cardiomyopathy is varying phenotypic expression. Even with identi... read more here.
Keywords: abstract 14308; epigenomic analysis; 14308 integrative; identifies enhancer ... See more keywords