Integrative Multi-Omics Through Bioinformatics.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-98758-3_5
Abstract: This chapter introduces different aspects of bioinformatics with a brief discussion in the systems biology context. Example applications in network pharmacology of traditional Chinese medicine, systems metabolic engineering, and plant genome-scale modelling are described. Lastly,… read more here.
Keywords: medicine; multi omics; omics bioinformatics; biology ... See more keywords
Abstract C034: Beyond genomics: Integrative multi-omics in cancer research
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-25-c034
Abstract: The treatment of cancer increasingly leverages genomic testing to tailor therapies to a patient's tumor profile. While this approach has achieved significant success, challenges and unmet needs remain. Integrating genomics with other "omics," particularly proteomics… read more here.
Keywords: cancer; multi omics; research; genomics integrative ... See more keywords
Abstract 409: Deciphering chromosomal instability in consensus molecular subtypes (CMS) in CRC: Insights from an integrative multi-omics approach
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-409
Abstract: CRC is a heterogeneous disease with different molecular subtypes, which can have a profound impact on treatment response and patient outcomes. CMS classification based on gene expression profiles has been shown to differentiate patients into… read more here.
Keywords: chromosomal instability; multi omics; multi; cms ... See more keywords
Defense dynamics in walnut (Juglans regia L.) fruit during walnut husk fly (Rhagoletis completa Cresson) infestation: an integrative, multi-level analysis
Sign Up to like & getrecommendations! Published in 2025 at "BMC Plant Biology"
DOI: 10.1186/s12870-025-07552-0
Abstract: The walnut husk fly (WHF) is a critical pest affecting global walnut production, causing economic losses of up to 80%. WHF larvae feed within the walnut husk, creating necrotic spots, which compromise kernel quality and… read more here.
Keywords: integrative multi; fruit; walnut; walnut husk ... See more keywords
Integrative multi-omics framework for causal gene discovery in Long COVID
Sign Up to like & getrecommendations! Published in 2025 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1013725
Abstract: Long COVID, or Post-Acute Sequelae of SARS-CoV-2 infection (PASC), affects an estimated 10–20% of COVID-19 patients and presents persistent multisystemic symptoms. Although demographic and clinical factors, such as age, sex, and comorbidities, contribute to risk,… read more here.
Keywords: causal gene; multi omics; omics framework; integrative multi ... See more keywords
Integrative Multi-Omics Reveals Serum Markers of Tuberculosis in Advanced HIV
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.676980
Abstract: Tuberculosis (TB) accounts for disproportionate morbidity and mortality among persons living with HIV (PLWH). Conventional methods of TB diagnosis, including smear microscopy and Xpert MTB/RIF, have lower sensitivity in PLWH. Novel high-throughput approaches, such as… read more here.
Keywords: multi omics; hiv; plwh; advanced hiv ... See more keywords
Integrative multi-omics analysis reveals the interaction mechanisms between gut microbiota metabolites and ferroptosis in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1608262
Abstract: Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis and joint destruction. To systematically investigate the regulatory relationship between key ferroptosis genes and gut metabolites in RA, this study employed an integrative… read more here.
Keywords: multi omics; analysis; ferroptosis; rheumatoid arthritis ... See more keywords
Genetic Alterations of SMYD4 in Solid Tumors Using Integrative Multi-Platform Analysis
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25116097
Abstract: SMYD4 is a member of the SMYD family that has lysine methyltransferase function. Little is known about the roles of SMYD4 in cancer. The aim of this study is to investigate genetic alterations in the… read more here.
Keywords: multi platform; solid tumors; genetic alterations; alterations smyd4 ... See more keywords
Recent Advances in Integrative Multi-Omics Research in Breast and Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm11020149
Abstract: The underlying molecular heterogeneity of cancer is responsible for the dynamic clinical landscape of this disease. The combination of genomic and proteomic alterations, including both inherited and acquired mutations, promotes tumor diversity and accounts for… read more here.
Keywords: advances integrative; breast ovarian; ovarian cancer; recent advances ... See more keywords