Integrative Omics for Identifying Dysfunctional Pathways in CKD
Sign Up to like & getrecommendations! Published in 2019 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2018.12.009
Abstract: T he mechanisms underlying chronic kidney disease (CKD) remain poorly understood, and treatments to prevent or forestall CKD progression are limited. Precision medicine aims to change this. Advances in high-throughput technologies have already led to… read more here.
Keywords: integrative omics; pathways ckd; dysfunctional pathways; identifying dysfunctional ... See more keywords
Putting Genes In Context: Applying Integrative 'Omics To Alcohol Use Disorder
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.06.076
Abstract: Abstract Alcohol misuse is the 4th leading cause of preventable mortality in the United States and contributes to over 3 million deaths worldwide each year. The use of alcohol in a pathologic fashion, alcohol use… read more here.
Keywords: integrative omics; use; alcohol; alcohol use ... See more keywords
An integrative omics approach to unravel toxicity mechanisms of environmental chemicals: effects of a formulated herbicide
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29662-6
Abstract: The use of integrative molecular approaches can aid in a comprehensive understanding of the effects of toxicants at different levels of biological organization, also supporting risk assessment. The present study aims to unravel the toxicity… read more here.
Keywords: integrative omics; reproduction; toxicity; unravel toxicity ... See more keywords
Integrative Omics: Harnessing the Proteome to Maximize the Potential of the Genome
Sign Up to like & getrecommendations! Published in 2018 at "Circulation"
DOI: 10.1161/circulationaha.117.032807
Abstract: Article, see p 1158 Great strides have been made in dissecting the genetics of cardiovascular disease (CVD) through genome-wide association studies and whole exome/genome sequencing, although the full heritability remains to be elucidated. Furthermore, biological… read more here.
Keywords: integrative omics; omics harnessing; disease; cvd ... See more keywords
Integrative OMICS Data-Driven Procedure Using a Derivatized Meta-Analysis Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.828786
Abstract: The wealth of high-throughput data has opened up new opportunities to analyze and describe biological processes at higher resolution, ultimately leading to a significant acceleration of scientific output using high-throughput data from the different omics… read more here.
Keywords: meta analysis; methodology; large scale; meta ... See more keywords