Integrin Catch Bond Kinetics Mediate Mechanosensing during Cell Spreading
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DOI: 10.1016/j.bpj.2016.11.189
Abstract: Cell spreading and polarization are morphogenetic responses to extracellular matrix adhesion. Cultured fibroblasts polarize when plated on rigid, but not compliant substrates. In this study, we demonstrate that fibroblasts have increased spread area on compliant… read more here.
Keywords: bond kinetics; integrin catch; catch bond; cell spreading ... See more keywords