Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c08367
Abstract: As effective ways to regulate protein levels, targeted protein degradation technologies have attracted great attention in recent years. Here, we established a novel integrin-facilitated lysosomal degradation (IFLD) strategy to degrade extracellular and cell membrane proteins… read more here.
Keywords: targeted protein; protein degradation; protein; degradation ... See more keywords