SIN3B promotes integrin αV subunit gene transcription and cell migration of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjy050
Abstract: Abstract Paired amphipathic helix protein (SIN3B) is a transcription corepressor for many genes. Here we show a different regulation mechanism of integrin αV gene expression by SIN3B in human hepatocellular carcinoma (HCC). We first observed… read more here.
Keywords: hepatocellular carcinoma; sin3b; integrin subunit; gene ... See more keywords
Application of integrin subunit genes in pancreatic cancer and the construction of a prognosis model
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-24-612
Abstract: Background Pancreatic adenocarcinoma (PAAD) is a highly aggressive malignant tumor with a poor prognosis. Integrin subunit genes (ITGs) serve as biomarkers for various types of cancers; however, to date, no prognostic research has been conducted… read more here.
Keywords: integrin subunit; subunit genes; prognosis; prognosis model ... See more keywords
Integrin subunit alpha V is a potent prognostic biomarker associated with immune infiltration in lower-grade glioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.964590
Abstract: As a member of integrin receptor family, ITGAV (integrin subunit α V) is involved in a variety of cell biological processes and overexpressed in various cancers, which may be a potential prognostic factor. However, its… read more here.
Keywords: infiltration; integrin subunit; expression; glioma ... See more keywords
Comprehensive Characterization of Integrin Subunit Genes in Human Cancers
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.704067
Abstract: Although integrin subunit genes (ITGs) have been reported to be associated with some human cancer types, a systematic assessment of ITGs across human cancers is lacking. Hence, we performed comprehensive analyses to investigate mRNA expression,… read more here.
Keywords: cancer types; human cancers; integrin subunit; cancer ... See more keywords
Integrin Subunit Alpha M, ITGAM Nonsynonymous SNP Is Associated with Knee Osteoarthritis among Thais: A Case-Control Study
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45050265
Abstract: Knee osteoarthritis (OA), which is one of the most common degenerative joint diseases, presents a multifactorial etiology, involving multiple causative factors including genetic and environmental determinants. Four human neutrophil antigen (HNA) systems can be determined… read more here.
Keywords: control study; subunit alpha; knee osteoarthritis; integrin subunit ... See more keywords
Low, but Not High, Pulsating Fluid Shear Stress Affects Matrix Extracellular Phosphoglycoprotein Expression, Mainly via Integrin β Subunits in Pre-Osteoblasts
Sign Up to like & getrecommendations! Published in 2024 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb46110738
Abstract: Matrix extracellular phosphoglycoprotein (Mepe), present in bone and dentin, plays important multifunctional roles in cell signaling, bone mineralization, and phosphate homeostasis. Mepe expression in bone cells changes in response to pulsating fluid shear stress (PFSS),… read more here.
Keywords: integrin subunit; high pfss; pfss; pre osteoblasts ... See more keywords