Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression
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DOI: 10.1038/onc.2017.248
Abstract: Glioblastoma (GBM) is a primary brain cancer that contains populations of stem-like cancer cells (GSCs) that home to specialized perivascular niches. GSC interactions with their niche influence self-renewal, differentiation and drug resistance, although the pathways… read more here.
Keywords: signaling axis; tgf; progression; integrin tgf ... See more keywords