Gut Microbiome and Metabonomic Profile Predict Early Remission to Anti-Integrin Therapy in Patients with Moderate to Severe Ulcerative Colitis
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DOI: 10.1128/spectrum.01457-23
Abstract: It is reported that patients with ulcerative colitis (UC) have low response rates to anti-integrin medications in the latest VARSITY study. Therefore, our primary goals were to discover differences in the gut microbiome and metabonomics… read more here.
Keywords: early remission; integrin therapy; remission; anti integrin ... See more keywords
Anti-integrin therapy for inflammatory bowel disease
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DOI: 10.3748/wjg.v24.i17.1868
Abstract: In inflammatory bowel disease (IBD), tumor necrosis factor plays an important role in mediating inflammation, but several other pathways are also involved in eliciting an inflammatory response. One such pathway is the invasion of the… read more here.
Keywords: anti integrin; bowel disease; inflammatory bowel; integrin ... See more keywords