Articles with "integrity checkpoints" as a keyword



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Cerium Oxide Nanoparticles Re-establish Cell Integrity Checkpoints and Apoptosis Competence in Irradiated HaCat Cells via Novel Redox-Independent Activity

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Published in 2018 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2018.01183

Abstract: Cerium oxide nanoparticles (CNPs) are potent radical scavengers protecting cells from oxidative insults, including ionizing radiation. Here we show that CNPs prevent X-ray-induced oxidative imbalance reducing DNA breaks on HaCat keratinocytes, nearly abating mutagenesis. At… read more here.

Keywords: cell integrity; cerium oxide; irradiated hacat; oxide nanoparticles ... See more keywords